Bisa kididdigar da Zhiliwo Big Data Platform ta yi, matsakaicin tasirin tasirin ambaton takardun Foregene SCI a watan Fabrairun 2022 ya kai 5.8, kuma mafi girman tasirin tasirin shine 8.947.
Ta hanyar ƙididdigar ƙididdiga na adadin takaddun SCI na samfuran Foregene a cikin shekaru, an gano cewa haɓakar haɓaka a bayyane yake.
Foregene Co., Ltd an kafa shi a cikin 2011. Yana da sana'ar fasahar kere kere da ke haɗa R&D, samarwa, tallace-tallace da sabis na abokin ciniki.Tun lokacin da aka kafa shi, yana mai da hankali kan haɓaka fasahar kwayoyin halitta da tantanin halitta da ke da alaƙa, samfura da ayyuka, da samar da tsarkakewar acid nucleic, gano nucleic acid da sauran mafita ga yawancin masu amfani.Layin binciken kimiyyar sa ya haɗa da jerin tsarkakewa na RNA, jerin tsarkakewar DNA, jerin RT/RT-PCR, jerin PCR kai tsaye, jerin PCR Mix, jerin RT-qPCR kai tsaye da jerin kayan aikin “Sui”.An yi amfani da samfuran sosai a cikin bincike na asali a fannonin kimiyyar rayuwa, likitanci, aikin gona, magunguna, da muhalli.Abokan ciniki suna cikin jami'o'i, cibiyoyin bincike, asibitoci da sauran sassan.
ZhiLiaowo ya zaɓi manyan takardu 6 na Foregene a watan Fabrairu don yin la'akari da masu bincike, don samun zurfin fahimta da sanin samfuran Foregene.
Taken labarin: Ƙunƙarar ƙwanƙwasa tana daidaita bambance bambancen ɓangarorin ƙwararrun ƙwararrun ƙwararrun ƙwararrun ƙwararrun ƙwararrun ƙwararrun ƙwanƙolin zuciya.
DOI: 10.1016/j.actbio.2022.02.032
Lokacin fitarwa: 2022-2-27
Foregene
Kayayyakin Littattafai da aka kawo
Taken Labari: Gano Mahimman Sa hannun Mitochondrial Proteome Haɗe da Haɗawa da Ciwon Jiji na Jijiyoyin Jiji a cikin Model Rat
DOI: 10.1155/2022/8401924
Lokacin fitarwa: 2022-2-21
Alakar marubuci: Sashen kantin magani, Asibitin Farko na Jami'ar Kiwon Lafiya ta Xinjiang.
Abstract: Hawan jini na huhu (PAH) cuta ce mai tsanani kuma mai ci gaba da ta shafi zuciya da huhu kuma matsala ce ta lafiyar duniya da ke damun mutane da al'umma.A cikin wannan binciken, an yi nasarar gina samfurin bera na PAH wanda monocrotaline (MCT) ya jawo.An ƙaddara sunadaran mitochondrial na kowane rukuni na berayen ta hanyar amfani da dabarun ƙididdige ƙididdiga marasa lakabi.Dangane da ginawa da haɓaka aiki na hanyoyin sadarwa na furotin-protein (PPI), 19 da aka tsara tsarin mitochondrial da 123 da aka tsara na mitochondrial genes an duba su a cikin berayen PAH.Bugu da ƙari, a cikin gwajin gwaji mai zaman kanta na ƙungiyoyi masu zaman kansu, sakamakon ya nuna cewa 6 da aka tsara na mitochondrial genes da 3 da aka tsara na mitochondrial genes an nuna su daban-daban a cikin ƙwayar huhu na ratsan PAH.An yi hasashen yiwuwar miRNA-niyya na tsakiyar mitochondrial genes a matakin rubutu ta amfani da bayanan RNAInter.Har ila yau, binciken ya gano bortezomib da carfilzomib a matsayin magunguna masu mahimmanci don maganin PAH.A ƙarshe, wannan binciken yana ba da sabon haske kan maɓalli masu alamar halitta da dabarun warkewa ga PAHs.
Foregene
Kayayyakin Littattafai da aka kawo
RT Easy II (Master Premix for First Strand cDNA Synthesis For qPCR)
Saukewa: RT-01021
Musammantawa: 50 × 10 μL rxns
Taken Labari: PTEN hasara yana ba da hankali ga rapalogs a cikin ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta
DOI: 10.1038/s41401-022-00862-1
Lokacin fitarwa: 2022-2-14
Haɗin marubuci: Sashen kantin magani, Asibitin Nanfang, Jami'ar Kiwon Lafiya ta Kudancin, Guangzhou, China
Abstract: Rapalog allosteric mTORC1 inhibitor ne kuma an yarda da magani don ci-gaba bayyanannen ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta (ccRCC).Nazarin ta yin amfani da layukan tantanin halitta na ccRCC masu haƙuri da yawa sun nuna cewa ƙwayoyin ƙarancin PTEN suna nuna rashin jin daɗi ga rapalogs.A cikin layukan salula na ccRCC na PTEN-rauni, Rapalogs sun hana yaduwar kwayar halitta ta hanyar haifar da kama G0/G1 ba tare da haifar da apoptosis ba.Yin amfani da CRISPR / Cas9-haɓaka layin salula na isogenic, binciken ya tabbatar da haɗin gwiwa tsakanin shafewar PTEN da Rapallo hypersensitivity.Sabanin haka, shafewar VHL ko chromatin-gyaran kwayoyin halitta (PBRM1, SETD2, BAP1, ko KDM5C) bai shafi martanin salula ga rapalogs ba.Maganar Ectopic na wani mutant mTOR da aka kunna (C1483F) an nuna shi don magance PTEN da ke haifar da haɓakar haɓakar ƙwayar ƙwayar cuta, yayin da gabatarwar kwayar cutar ta mTOR (A2034V) ta ba da damar PTEN-rashin ccRCC sel don guje wa tasirin haɓaka-suppressive na rapalogs.Kwayoyin ccRCC masu ƙarancin PTEN sun fi kula da tasirin hanawa na temsirolimus akan ƙaurawar tantanin halitta da haɓakar ƙari a cikin zebrafish da mice xenograft.Nazarin ya nuna cewa shafewar PTEN yana da alaƙa da ƙwarewar rapallo kuma ana iya amfani dashi azaman alama don zaɓin maganin rapallo a cikin marasa lafiya na ccRCC.
Foregene
Kayayyakin Littattafai da aka kawo
Taken labarin: Tsarin ƙarfi na microbiota na ruwan sharar ruwa mai yawan salinity tare da yisti mai jurewa gishiri da aikace-aikacen sa.
DOI: 10.1016/j.jece.2022.107377
Lokacin fitarwa: 2022-2-12
Ƙungiyar marubuci: Makarantar Kimiyyar Rayuwa, Jami'ar Al'ada ta Jiangxi
Abstract: Ruwan dattin ruwa mai yawan gishiri shine ruwan sharar masana'antu tare da hadaddun abubuwa, rashin lafiyar biodegradable da wahalan maganin biochemical.Don bayyana ainihin tsarin ƙwayoyin cuta na al'umma a cikin kula da babban salinity kwayoyin datti ta hanyar gishiri mai jurewa da yisti, an gudanar da nazarin halayyar ƙananan ƙwayoyin cuta da abubuwan muhalli.Ƙimar kawar da buƙatar iskar oxygen, NH3-H da jimlar nitrogen an inganta sosai a cikin ma'aunin matukin jirgi na WWTP.Sakamako mai girma-sakamako ya nuna cewa biofortification yana tasiri sosai ga tsarin al'umma.A matakin phylum, ƙungiyoyin Proteobacteria da Ascomycota sun fi yawa, yayin da a matakin jinsin Paracoccus da Meyeroi suka mamaye.Meyerella yana taka muhimmiyar rawa wajen kula da ruwa mai tsabta na kwayoyin halitta, wanda zai iya zama babban dalili na ingantaccen kawar da gurɓataccen abu.Bugu da ƙari, pH, narkar da iskar oxygen, da kuma tasiri mai tasiri sune mahimman abubuwan da suka shafi sauye-sauyen al'ummomin microbial a yayin da ake yin bioaugmentation, duk da haka, yawan Meyerrotheca bai shafe shi ba ta hanyar tasiri mai yawa.Wannan binciken da aka tsara ya bayyana canje-canje masu ƙarfi da tsinkayar aiki na ƙananan ƙwayoyin cuta yayin bioaugmentation, da kuma alaƙar da ke tsakanin al'ummomin ƙananan ƙwayoyin cuta da abubuwan muhalli, da kafa tushe mai tushe na ka'ida don kula da ruwa mai zurfi da gishiri mai girma.
Foregene
Kayayyakin Littattafai da aka kawo
Taken Labari: Multi-Omics Analysis Bayan Gudanarwar Farji na Bacteroides fragilis a cikin Kaji.
DOI: 10.3389/fmicb.2022.846011
Lokacin fitarwa: 2022-2-16
Haɗin mawallafi: Babban dakin gwaje-gwaje na Sichuan na ci gaban albarkatun gona da kwayoyin dabbobi da haɓakawa
Abstract: Fannin haihuwa na kaji wata muhimmiyar gaba ce ta samuwar kwai.Matsakaicin kusanci tsakanin farji da yanayin waje na iya haifar da mamaye nau'ikan kwayoyin cuta daban-daban, suna shafar ingancin ciki da waje, har ma da karuwar mace-mace da haifar da asarar tattalin arziki.A cikin 'yan shekarun nan, probiotics sun kawo fa'idodin tattalin arziki ga dabbobi da kiwon kaji a matsayin madadin maganin rigakafi.Sakamakon gudanar da aikin farji na B. fragilis akan kajin cloacal microbiota, transcriptome na farji da metabolome an bincika don tantance yiwuwar amfani na B. fragilis.Sakamakon ya nuna cewa jiyya na B. fragilis ya shafi ƙananan ƙwayoyin cuta na cloaca.Binciken fassarar ya gano cewa kwayoyin halittar CCN3, HAS2, da RICTOR da ke da alaka da rigakafi an daidaita su, kuma kwayoyin cutar EDNRB, TOX, da NKX2-3 sun kasance marasa tsari, kuma DEGs kuma sun wadatar da tsarin kumburi, metabolism na salula, da hanyoyin amsawar synaptic.Bugu da ƙari, bambance-bambancen metabolites sun fi dacewa da biosynthesis na hormone steroid, unsaturated fatty acid biosynthesis, da arachidonic acid metabolism, kuma binciken ya gano ƙungiyoyi tsakanin takamaiman metabolites da kwayoyin halitta.A ƙarshe, wannan binciken yana ba da tushen ka'idar don aikace-aikacen B. fragilis a matsayin yuwuwar probiotic a cikin dabbobi da kiwon kaji.
Foregene
Kayayyakin Littattafai da aka kawo
RT Easy II (Master Premix don haɗin cDNA na farko don qPCR)
Lambar kwanan wata: RT-01031
Musammantawa: 25 × 20 μL rxns
Taken labarin: Bambance-bambancen halittar Echinococcus granulosus sensu lato a kasar Sin: nazarin cututtukan cututtuka da nazari na tsari
DOI: 10.1111/tbed.14469
Lokacin fitarwa: 2022-2-9
Haɗin mawallafi: Babban dakin gwaje-gwaje na Sichuan na ci gaban albarkatun gona da kwayoyin dabbobi da haɓakawa
Abstract: Cystic echinococcosis (CE) cuta ce ta zoonotic na wurare masu zafi da aka yi watsi da ita ta Echinococcus granulosus kuma ta kasance babbar matsalar lafiyar jama'a ta duniya.An gano wasu sanannun nau'in halittar Echinococcus granulosus ban da G4 a kasar Sin, musamman ma yankin Qinghai-Tibet Plateau, kuma bambancin jinsin su ya kasance na musamman a wannan yanki na duniya.Bisa ga nazari na yau da kullum, tsarin kwayoyin halitta na E. granulosa a cikin ƙasata shine kamar haka: E. granulosa (G1, G3), 98.3%;Echinococcus intermedius (G5), 0.1%;Echinococcus intermedius (G6, G7), 1.4%;da Canada Echinococcus (G8, G10), 0.2%.Musamman, adadin kamuwa da cuta na G1 ya kasance 97.7% kuma ana siffanta shi da kewayon mai watsa shiri da rarraba yanki.Sakamakon cututtukan cututtuka ya nuna ingantaccen tsarin halittar E. coli mai kyau a cikin tumaki da yak daga larduna uku masu girma na CE (Xinjiang, Sichuan, da Qinghai).Tumaki (287/406, 70.7%) suna da mafi girman rabo na cysts masu haihuwa fiye da yak (28/184, 15.2%).A cikin shekaru 29 da suka gabata, an sami Echinococcus granulosus cox1 haplotypes 51 a kasar Sin.Halin haplotype na kakanni (Hap_2) ya kasance mafi yawan haplotype, 12 na yau da kullun na haplotypes sun kasance endemic, kuma an gano sabbin nau'ikan haplotype guda 9 yayin binciken.Sakamakon binciken ya nuna cewa wajabcin rigakafi na tumaki da yaƙin neman zaɓe na rigakafin EG95 na yaks sun yi daidai da halin da ake ciki yanzu.
Foregene
Kayayyakin Littattafai da aka kawo
Tuntuɓar:
Maggie |Ci gaban Kasuwanci
Foregene Co., Ltd
Saukewa: +86-15281067355
URL: www.foreivd.com
Lokacin aikawa: Afrilu-08-2022
